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Type Product title / description Pub Price
Expert View
Expert View

Xarelto data raise questions at the 2010 American Heart Association Scientific Sessions

Results from the ROCKET-AF trial of Xarelto in stroke prevention in atrial fibrillation have been presented at this year's Scientific Sessions of the American Heart Association. While positive, the data show that Xarelto has by no means outperformed Pradaxa. Clinicians may start to see the two drugs as complementary alternatives, based on their respective performance in various subgroups.

Published By Datamonitor
16 Nov 2010
CommentWire
CommentWire

Xanthus: more hurdles to clear for Symadex

Xanthus Life Sciences has begun dosing patients in a phase II trial of Symadex in recurrent colorectal cancer. While this is clearly a positive step in Symandex' development, the drug candidate still has phase III trials to contend with and, even if Symandex proves fit for launch here, Xanthus will need to find a marketing partner to help it achieve commercial success in the tough cancer market.

Published By Datamonitor
17 Jan 2006
CommentWire
CommentWire

Xanthus Pharmaceuticals: trial hopes to meet unmet need in secondary leukemia

Xanthus Pharmaceuticals has begun patient dosing in a Phase III trial of its drug Xanafide. Patients with secondary acute myeloid leukemia are poorly served by existing drug therapy; physicians are therefore likely to be enthusiastic about a drug which can improve treatment outcomes. At this stage of development, however, it is too early to forecast the chances of Xanthus's drug being successful.

Published By Datamonitor
10 Oct 2007
CommentWire
CommentWire

Wyevale: room to grow

Sir Tom Hunter and Baugur are leading a consortium to take over Wyevale Garden Centres in a deal that values the UK's largest garden retailer at GBP310 million. Despite a recent downturn in sales, the underlying prospects for the retailer are promising and the investment could drive further growth.

Published By Datamonitor
21 Apr 2006
CommentWire
CommentWire

Wyeth: yet more bad news for Pristiq

The termination of Pristiq for fibromyalgia represents another setback for Wyeth, which had high hopes for its follow-on drug to Effexor. However, all is not lost as Wyeth's greatest commercial opportunity for Pristiq will be gained through indications for depression and menopausal symptoms, although heart and liver safety concerns added to regulatory delays may still limit the drug's potential.

Published By Datamonitor
10 Aug 2007
CommentWire
CommentWire

Wyeth: wider benefits for Prevnar

Research from Kaiser Permanente suggests that widespread immunization with Prevnar reduces the incidence of pneumococcal infections in adults and older children. This and other similar studies should help to establish greater demand for Prevnar, which has yet to entirely fulfill its potential due to its relatively high cost.

Published By Datamonitor
05 May 2004
CommentWire
CommentWire

Wyeth: WHI Premarin study stops early

The 2002 halt of the WHI study using Wyeth's [WYE] Prempro triggered heavy losses to Premarin family sales. Now the remaining study, including Premarin itself, has also come to an abrupt end due an increased risk of stroke. After losing around $1 billion of the brand's annual revenue since 2002, this slide is now unlikely to slow.

Published By Datamonitor
05 Mar 2004
CommentWire
CommentWire

Wyeth: UK offers Efexor relief

Having concluded a new review of the latest safety evidence related to Wyeth's serotonin and noradrenergic reuptake inhibitor Efexor, UK regulators have eased the barriers restricting use of the drug. The updated prescribing advice should help Wyeth stabilize sales of Efexor while also enabling the company to plan more effectively for the launch of its follow-on compound, desvenlafaxine.

Published By Datamonitor
02 Jun 2006
CommentWire
CommentWire

Wyeth: Torisel valuable for poor-risk patients

The European Commission has granted regulatory approval to Wyeth's Torisel, making it the first mTOR kinase inhibitor to reach the EU market. While renal cell carcinoma patients are becoming increasingly well served in terms of treatment options, Torisel represents a valuable addition for poor-risk patients, who traditionally have been the most difficult to treat.

Published By Datamonitor
27 Nov 2007
CommentWire
CommentWire

Wyeth: Prempro linked with dementia

A recent study published in the Journal of the American Medical Association has shown that Wyeth's hormone combination therapy Prempro increases the risk of probable dementia in postmenopausal women aged 65 years or older. Further studies are needed to establish the role of estrogen therapies in the onset of Alzheimer's disease.

Published By Datamonitor
29 May 2003

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