Opinion on Pharmaceuticals and Healthcare in North America

Published within

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Type Product title / description Pub Price
CommentWire
CommentWire

ZymoGenetics: rhThrombin has great potential

In line with the rapid historical uptake of other recombinant protein products, following an anticipated approval in late 2007, ZymoGenetics' rhThrombin is expected to quickly take market share from King Pharmaceutical's Thrombin-JMI. Upon doing so, rhThrombin's revenues are forecast to grow from $165 million in 2008 to an impressive $459 million in 2010, well ahead of Wall Street consensus.

Published By Datamonitor
13 Apr 2006
CommentWire
CommentWire

ZymoGenetics: early hope for late-stage disease

ZymoGenetics has reported positive results from its phase Ia study of IL-21 in patients with metastatic melanoma and metastatic renal cell carcinoma. This announcement warrants further studies of IL-21 in these indications, which is welcome news for ZymoGenetics and development partner Novo Nordisk. However, competition is already on the horizon, in the form of Bayer/Onyx' Nexavar.

Published By Datamonitor
15 Nov 2005
CommentWire
CommentWire

ZymeTx: flu management program could be catching

Published By Datamonitor
17 Apr 2001
CommentWire
CommentWire

Zimmer: the strong get stronger

Over the past few years, Zimmer [ZMH] has demonstrated even higher growth than the impressive rates seen in the overall orthopaedic market, and is now set to become even stronger with the addition of Centerpulse. The company will take market leadership position in joint reconstruction and become the fifth largest player in the lucrative sector of spinal implants.

Published By Datamonitor
20 Oct 2003
CommentWire
CommentWire

Zimmer: spinal expansion would maximize Collagraft potential

The recent approval for these indications allows Zimmer to compete in the largest segment of the $200 million US market for bone growth substitutes. However, unless the company fully enters the spinal implant market - including the establishment of a spinal salesforce - Collagraft will not reach its sales potential.

Published By Datamonitor
01 Nov 2001
CommentWire
CommentWire

Zimmer: big advances through tiny holes

Zimmer has released positive preliminary results for its two-incision minimally invasive hip arthroplasty system, and also plans to open a training facility teaching surgeons how to implant these systems. But while the system can radically reduce recovery time, it involves an extremely difficult technique that most orthopaedic surgeons are unlikely to adopt.

Published By Datamonitor
24 Jul 2002
Expert View
Expert View

Zelboraf's approval demonstrates a significant shift toward personalized cancer therapy

The FDA has approved Zelboraf and Roche's companion diagnostic test for BRAF V600E mutation-positive metastatic melanoma. The joint approval is the first example of co-development and demonstrates the movement toward personalized cancer therapy, and Zelboraf's impressive efficacy data and the availability of a test will ensure rapid uptake.

Published By Datamonitor
18 Aug 2011
CommentWire
CommentWire

Yahoo/CIGNA: taking prescription benefit information online

The new service should cut the costs associated with the retrieval of benefits information, including call center costs. It should also improve service and information accuracy for CIGNA employers and members. For pharma companies, it is likely to enhance treatment compliance and make the ordering of prescription drugs more efficient.

Published By Datamonitor
11 Jan 2002
CommentWire
CommentWire

Xolair: breathing easy over FDA approval

Xolair, developed by Genentech, Novartis and Tanox, reduces the number of attacks in severe allergic asthmatics. However prescribing restrictions, safety concerns and high cost are expected to limit sales to $593 million by 2010. The drug's best chance of success is through label extensions for pediatric use and for allergic rhinitis.<BR />

Published By Datamonitor
19 May 2003
Expert View
Expert View

Xigris: struggling to overcome its problems

The once lauded drug Xigris is struggling to recover from a series of setbacks, despite existing in a potentially lucrative market with little competition. After disappointing US sales, Xigris has now been launched in Europe. Datamonitor's Michael Randle asks if Eli Lilly can take advantage of its status as the only approved severe sepsis treatment and breathe new life into its sleeping giant.

Published By Datamonitor
15 Nov 2002

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