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Expert View
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Results from the ROCKET-AF trial of Xarelto in stroke prevention in atrial fibrillation have been presented at this year's Scientific Sessions of the American Heart Association. While positive, the data show that Xarelto has by no means outperformed Pradaxa. Clinicians may start to see the two drugs as complementary alternatives, based on their respective performance in various subgroups.
Published By Datamonitor
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16 Nov 2010 |
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CommentWire
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Wyeth has announced new positive Phase III data for its menopause treatment Aprela. The potential blockbuster is well positioned to provide a unique approach to the treatment of menopausal symptoms in women at risk of developing osteoporosis, and assuming regulatory hurdles can be overcome, Aprela will help further maintain Wyeth's position as a leading women's health player.
Published By Datamonitor
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29 Jul 2009 |
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CommentWire
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Wyeth's performance in 2002 was negatively affected by its heavy reliance on its Women's Health franchise. With the anticipated launch of Flumist, it is expected that 2003 will mark the beginning of Wyeth's transition from a reliance on HRT treatments to a more diversified portfolio.<BR />
Published By Datamonitor
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05 Jun 2003 |
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CommentWire
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The current economic environment has paved the way for leading pharmaceutical firms to sweep in and buy up smaller players, highlighted by Wyeth's potential acquisition of Crucell and Merck & Co's strategy to aggressively look for targets in 2009. An increasing number of pharmaceutical majors are likely to use this approach to strengthen their biologic portfolios and access novel pipeline drugs.
Published By Datamonitor
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09 Jan 2009 |
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Expert View
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Datamonitor attended this year's International Osteoporosis Foundation World Congress on Osteoporosis and 10th European Congress on Clinical and Economical Aspects of Osteoporosis and Osteoarthritis, the most important meeting on the osteoporosis calendar. A number of major pharmaceutical firms had a presence at the meeting, indicating the significance of this market.
Published By Datamonitor
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18 May 2010 |
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Expert View
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Although the contraceptive pill has been hugely successful, remembering to take it every day can be a problem. Alternative delivery methods such as implants and injections, meanwhile, have proved unpopular. The contraceptive patch could fill the middle ground, potentially cutting unwanted pregnancies - but will it? Datamonitor women's health analyst Jane Richardson cuts through the hype...
Published By Datamonitor
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28 Mar 2002 |
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CommentWire
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Vertex has completed a Phase II trial of a small-molecule oral drug, VX-770, which targets the basic defect that occurs in cystic fibrosis (CF). The trial has only been performed in 20 patients from a small, genetically distinct subset of the CF population. However, the results are encouraging and indicate an alternative approach to traditional reactive management of CF.
Published By Datamonitor
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28 Mar 2008 |
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CommentWire
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Vertex Pharmaceuticals' novel cystic fibrosis treatment VX-770 has demonstrated strong efficacy in a Phase III trial, meeting the primary endpoint and key secondary endpoints. VX-770 targets the underlying cause of the disease, and, if approved, would offer a novel treatment approach.
Published By Datamonitor
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25 Feb 2011 |
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CommentWire
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New phase III data have confirmed previous results showing Vernalis and Endo's Frova to be an effective preventative treatment for menstrual migraine. This should pave the way for the migraine drug's approval in this additional indication. Anticipated in 2007, this approval is then expected to transform Frova's sales significantly.
Published By Datamonitor
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08 May 2006 |
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Expert View
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Amgen has received a positive opinion from the CHMP for Vectibix in combination with chemotherapy in the first- and second-line treatment of mCRC. This is a significant step forward for Vectibix, but if it is approved, market competition will result in only a modest increase in uptake and commercial reward.
Published By Datamonitor
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27 Jun 2011 |
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